Do not use BuSpar if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, and tranylcypromine.
To make sure BuSpar is safe for you, tell your doctor if you have any of these conditions:
- kidney disease; or
- liver disease.
FDA pregnancy category B. BuSpar is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.[/vc_column_text][/vc_tta_section][vc_tta_section title=”Use” tab_id=”1500389328750-d09ab9ad-1d93″][vc_column_text]Take BuSpar exactly as it was prescribed for you. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended. You may take BuSpar with or without food but take it the same way each time. Some BuSpar tablets are scored so you can break the tablet into 2 or 3 pieces in order to take a smaller amount of the medicine at each dose. Do not use a tablet if it has not been broken correctly and the piece is too big or too small. Follow your doctor’s instructions about how much of the tablet to take. If you have switched to BuSpar from another anxiety medication, you may need to slowly decrease your dose of the other medication rather than stopping suddenly. Some anxiety medications can cause withdrawal symptoms when you stop taking them suddenly after long-term use. This medication can cause false positive results with certain medical tests. You may need to stop using the medicine for at least 48 hours before your test. Tell any doctor who treats you that you are using BuSpar. Store at room temperature away from moisture, heat, and light.[/vc_column_text][/vc_tta_section][vc_tta_section title=”How to Take” tab_id=”1500389387696-bdbeacb1-9ee0″][vc_column_text]This drug should be taken orally with a glass of water. Buspar can be taken with or without food in the system, but make sure you stick to your choice, if you decide to take it without food, maintain it as such and vice versa. Make sure you follow the prescription from your doctor. At times there are tablets which have been scored, enabling users to break the tablet into 3 or 2 pieces so as to minimize the amount of medicine taken per dose, ensure the tablet is broken as prescribed by the doctor, don’t take smaller or larger amounts of the tablet at any given time.[/vc_column_text][/vc_tta_section][vc_tta_section title=”Side Effects” tab_id=”1500389412853-d02a327a-b319″][vc_column_text]In addition to its needed effects, some unwanted effects may be caused by buspirone (the active ingredient contained in BuSpar). In the event that any of these side effects do occur, they may require medical attention. More common:Restlessness, nervousness, or unusual excitement Less common or rare Blurred vision, clamminess or sweating, decreased concentration, diarrhea, drowsiness, dryness of the mouth, muscle pain,spasms, cramps, or stiffness, ringing in the ears, trouble with sleeping, nightmares, or vivid dreams, unusual tiredness or weakness[/vc_column_text][/vc_tta_section][vc_tta_section title=”Precautions” tab_id=”1500389436547-e45a2b4c-4cda”][vc_column_text]Studies indicate that BuSpar (buspirone) is less sedating than other anxiolytics and that it does not produce significant functional impairment. However, its CNS effects in any individual patient may not be predictable. Therefore, patients should be cautioned about operating an automobile or using complex machinery until they are reasonably certain that buspirone treatment does not affect them adversely. While formal studies of the interaction of BuSpar (buspirone hydrochloride) with alcohol indicate that buspirone does not increase alcohol-induced impairment in motor and mental performance, it is prudent to avoid concomitant use of alcohol and buspirone.[/vc_column_text][/vc_tta_section][vc_tta_section title=”Drug Interactions” tab_id=”1500389457813-0dc3e294-95e1″][vc_column_text]MAO inhibitors: It is recommended that BuSpar (buspirone) not be used concomitantly with MAO inhibitors (see WARNINGS). Amitriptyline: After addition of buspirone to the amitriptyline dose regimen, no statistically significant differences in the steady-state pharmacokinetic parameters (Cmax, AUC, and Cmin) of amitriptyline or its metabolite nortriptyline were observed. Diazepam: After addition of buspirone to the diazepam dose regimen, no statistically significant differences in the steady-state pharmacokinetic parameters (Cmax, AUC, and Cmin) were observed for diazepam, but increases of about 15% were seen for nordiazepam, and minor adverse clinical effects (dizziness, headache, and nausea) were observed. Haloperidol: In a study in normal volunteers, concomitant administration of buspirone and haloperidol resulted in increased serum haloperidol concentrations. The clinical significance of this finding is not clear. Nefazodone: (see Inhibitors and Inducers of Cytochrome P450 3A4 [CYP3A4]) Trazodone: There is one report suggesting that the concomitant use of Desyrel® (trazodone hydrochloride) and buspirone may have caused 3- to 6-fold elevations on SGPT (ALT) in a few patients. In a similar study attempting to replicate this finding, no interactive effect on hepatic transaminases was identified. Triazolam/Flurazepam: Coadministration of buspirone with either triazolam or flurazepam did not appear to prolong or intensify the sedative effects of either benzodiazepine.[/vc_column_text][/vc_tta_section][/vc_tta_tabs][/vc_column][/vc_row]